Services
POLYMORPHISM SCREENING
Complete scientific support to discover and characterize the most relevant polymorphs of a drug
SALT SELECTION
Systematic salt screening studies to discover and select the salt derivative of an API
CO-CRYSTAL SCREENING
Co-crystals are an alternative to salts when these do not have the appropriate solid state properties or cannot be formed
Crystallization
Chiral Resolution
Crystallization
Crystallization of pharmaceutical compounds
Crysforma's extensive experience in crystallization of pharmaceutical compounds is used to successfully address complex crystallization challenges related to crystallization scale-up or to crystallization of poorly crystalline compounds.
Moreover, a unique combination of expertise and state-of-the-art instrumentation allows the structure determination of all types of small and medium sized molecules by single crystal X-ray diffraction (SCXRD) using crystals of reduced dimensions.
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Type of studies:
- Crystallization of compounds that are difficult to crystallize or that are formerly only known as amorphous solids
- Development and scale-up of robust crystallization procedures
- Crystallizations oriented to the generation of single crystals for SCXRD structure determination
- SCXRD structure determination of pharmaceutical organic molecules and natural products
- Direct absolute configuration determination of enantiomerically pure compounds
